Saturday, July 18, 2020

Caffeine acts as an adenosine-receptor antagonist

Adenosine is a central nervous system neuromodulator that has specific receptors. When adenosine binds to its receptors, neural activity slows down, and you feel sleepy. ... Caffeine acts as an adenosine-receptor antagonist. This means that it binds to these same receptors, but without reducing neural activity.

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Psychological aspects

The Striatum; part of the basal ganglia; neural pathways between the striatum and the frontal lobe have been implicated in planning function.

Planning is one of the executive functions of the brain, encompassing the neurological processes involved in the formulation, evaluation and selection of a sequence of thoughts and actions to achieve a desired goal. Various studies utilizing a combination of neuropsychological, neuropharmacological and functional neuroimaging approaches have suggested there is a positive relationship between impaired planning ability and damage to the frontal lobe.

A specific area within the mid-dorsolateral frontal cortex located in the frontal lobe has been implicated as playing an intrinsic role in both cognitive planning and associated executive traits such as working memory.

Disruption of the neural pathways, via various mechanisms such as traumatic brain injury, or the effects of neurodegenerative diseases between this area of the frontal cortex and the basal ganglia specifically the striatum (cortico-striatal pathway), may disrupt the processes required for normal planning function.

Individuals who were born Very Low Birth Weight (<1500 grams) and Extremely Low BirthWeight (ELBW) are at greater risk for various cognitive deficits including planning ability.

https://en.wikipedia.org/wiki/Planning

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Caffeine

An adenosine receptor antagonist is a drug which acts as an antagonist of one or more of the adenosine receptors. Examples include caffeine, theophylline, and theobromine.


Adenosine receptor antagonist - Wikipedia

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Adenosine Antagonists - an overview | ScienceDirect Topicswww.sciencedirect.com › topics › neuroscience › adenosi...

Caffeine, an adenosine antagonist, is the most widely used mood-altering drug in the world. Caffeine is rapidly absorbed and distributed throughout the body with ...

(Google)

Caffeine works for some with ADHD;  food additives in FDA approved medicines and foods need better ingredient labels.

- C. Thomas Wild (1981, 2020)

Insights into how words in a book become mental images, a block of clay becomes a sculpted figure:

- How To (Temporarily) Cure Hyperactivity book (about Inattentive ADHD relief) (Wild)
- Remarkable Medicine book (Dreyfus)
- Nerves in Collision book (Alvarez)
- The Hyperactive Child book (Renshaw)


(Partial Answers To Attentional Control Challenges)

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Caffeine reduces my appetite and increases my motivation. Is there a healthy alternative I can take that will do the same?


Compared to stronger stimulant, prescription only medicines (Ritalin, Dexedrine, Adderall, Vyvanse, etc.), caffeine is viewed as being healthier and safer. You can take a look at organic food, pure water, clean air, exercise, etc. Organic is good for overall health in general but that is quite different than falsely expecting organic foods to act like known stimulant drugs (like coffee, caffeine, Ritalin, Dexedrine, Adderall, Vyvanse, etc.). Some people choose to use caffeine; others choose not to use caffeine and make other choices. Stimulant medicines, including caffeine, do not work for everyone.

(Source:  E/a, q, other)

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